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US sets new gas-mileage rules

...Under the 1975 law that established fuel-economy rules, automakers must pay penalties if their vehicle lineups fail to meet the CAFE standard.

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Saunders: 'Inventor' crafts a following

...THE CHANNEL SWIM: In an announcement that's no surprise, Fox has renewed Prison Break for a second season under the title Prison Break-Manhunt.

The adventure will deal with the "constant pursuit" of the escaped heroes.

Don't look for the Emmy-winning Arrested Development, dropped by Fox, to move to Showtime.

Series creator Mitch Hurwitz will not be connected with the series if it has a future.

His announcement, in essence, ends the series, since Showtime had wanted Hurwitz to stay with the comedy.

TODAY'S NOSTALGIA: On March 30, 1966, CBS aired Barbra Streisand's second special, Color Me Barbra, directed by Dwight Hemion.

Saunders@RockyMountainNews.com or 303-892-5137 About Dusty Saunders Dusty Saunders is the television critic for the News.

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Nexavar Approved in Switzerland for the Treatment of Patients with ...

...In addition to company-sponsored trials, there are a variety of Nexavar studies being sponsored by government agencies, cooperative groups and individual investigators.Important Safety Considerations for U.S.

Patients Taking NexavarBased on the current, approved package insert for the treatment of patients with advanced kidney cancer, hypertension may occur early in the course of therapy and blood pressure should be monitored weekly during the first six weeks of therapy and treated as needed.

Incidence of bleeding regardless of causality was 15% for Nexavar vs.

8% for placebo and the incidence of treatment-emergent cardiac ischemia/infarction was 2.9% for Nexavar vs.

0.4% for placebo.

Most common treatment-emergent adverse events with Nexavar were diarrhea, rash/desquamation, fatigue, hand-foot skin reaction, alopecia, and nausea.

Grade 3/4 adverse events were 38% for Nexavar vs.

28% for placebo.

Women of child-bearing potential should be advised to avoid becoming pregnant and advised against breast-feeding.

In cases of any severe or persistent side effects, temporary treatment interruption, dose modification or permanent discontinuation should be considered.For U.S.

Nexavar prescribing information, visit http://www.nexavar.com or call 1.866.NEXAVAR (1.866.639.2827).Bayer/Onyx Co-DevelopmentNexavar is being co-developed by Bayer and Onyx.

The co-development collaboration calls for Onyx to fund 50 percent of the development a...

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