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Thermal Ablation Plus Radiation May Extend Lung Cancer Survival... Dupuy told Reuters Health. "This notion has far-reaching implications regarding future therapy for not only Dupuy of Rhode Island Hospital, Providence and colleagues treated 24 patients with inoperable NSCLC with CT-guided radiofrequency ablation followed by radiotherapy. The findings appear in the March issue of Chest.There were no treatment-related deaths or grade 3 or 4 toxicities. At a mean follow-up just over 2 years, 14 patients had died. The cumulative survival rate at 2 years was 50% and at 5 years, it was 39%.Ten deaths were cancer-related. Three patients died of respiratory failure with no evidence of active disease and another died of a cerebrovascular accident.Given these preliminary findings, the researchers just started a national multicenter trial in the hopes of improving survival in this group of patients."SOURCE:Chest 2006;129:738-745. "Reuters content
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